Viline-Met (50/1000mg) 14 Tablets

Overview

Viline-Met 50/1000mg is an oral anti-diabetic combination tablet intended for adults with type 2 diabetes mellitus when a clinician considers dual therapy appropriate. Each tablet strength indicates vildagliptin 50mg with metformin hydrochloride 1000mg. The combination is used alongside a diabetes care plan that may include diet control, regular physical activity, blood glucose monitoring and other medicines recommended by a healthcare professional.

Type 2 diabetes occurs when the body does not use insulin effectively and blood glucose remains higher than normal. Vildagliptin and metformin work through different mechanisms, so the combination may help improve glycaemic control in patients who are not adequately controlled on metformin alone or who are already using both medicines separately, subject to medical evaluation.

Benefits

• Helps improve glycaemic control in suitable adults with type 2 diabetes
• Combines two complementary anti-diabetic mechanisms in one tablet
• May be suitable for patients inadequately controlled on metformin alone when prescribed
• Can support simplified therapy for patients already using both components separately

Key Features

• Combination of vildagliptin 50mg and metformin hydrochloride 1000mg
• Oral tablet for adult type 2 diabetes mellitus
• Pack contains 14 tablets
• Used as part of a complete diabetes management plan
• Requires medical supervision and blood glucose monitoring

Dosage and How to Use

• How to use: Swallow the tablet with water. Take with or after food unless your doctor gives different instructions. Do not crush, split or chew unless advised by a healthcare professional.
• Administration: Oral administration only.
• Recommended dose: Use exactly as prescribed. For appropriate adults, vildagliptin/metformin fixed-dose combinations are commonly taken twice daily with meals, but the exact dose must be determined by the prescriber according to current therapy, kidney function and tolerability.
• Adult dose: As prescribed by the physician; commonly one tablet twice daily for patients suitable for the 50/1000mg strength.
• Pediatric use: Use in children and adolescents is not established; use only if specifically advised by a specialist.
• Elderly use: Older adults may require renal function assessment before and during therapy, and dose suitability should be reviewed by a doctor.
• When to take: Usually taken with meals to reduce metformin-related stomach upset, according to the dosing schedule prescribed by the doctor.
• With food: Take with or after food unless directed otherwise by a healthcare professional.
• Maximum daily dose: Do not exceed the dose prescribed by your doctor. Vildagliptin therapy commonly should not exceed 100mg per day; this strength provides 100mg vildagliptin and 2000mg metformin hydrochloride if taken twice daily.
• Missed dose: If a dose is missed, take it when remembered unless it is close to the next scheduled dose. Do not double the dose to make up for a missed tablet.
• Overdose: Seek urgent medical attention or contact a poison control centre if too many tablets are taken, especially if symptoms such as severe weakness, vomiting, abdominal pain, rapid breathing, confusion or low blood glucose occur.

Specifications

Side Effects

Common side effects

• Nausea
• Vomiting
• Diarrhoea
• Abdominal discomfort
• Loss of appetite
• Headache
• Dizziness
• Low blood glucose when combined with insulin or sulfonylureas

Serious side effects (seek medical help)

• Lactic acidosis symptoms such as severe weakness, deep or rapid breathing, unusual sleepiness, abdominal pain or low body temperature
• Pancreatitis symptoms such as severe persistent abdominal pain with or without vomiting
• Severe allergic reaction
• Liver-related symptoms such as yellowing of skin or eyes, dark urine or persistent nausea

Allergic reaction

Stop use and seek immediate medical help if swelling of the face, lips, tongue or throat, breathing difficulty, severe rash, itching or fainting occurs.

Safety and Precautions

• Use only under medical supervision for type 2 diabetes.
• Not for type 1 diabetes or diabetic ketoacidosis.
• Renal function should be assessed because metformin can accumulate in kidney impairment.
• Seek urgent care for symptoms of lactic acidosis, pancreatitis or severe allergic reaction.
• Tell your doctor about kidney, liver or heart problems before use.
• Inform your doctor before surgery or imaging procedures using iodinated contrast.
• Avoid dehydration and seek advice during severe vomiting, diarrhoea, fever or reduced fluid intake.
• Monitor blood glucose as advised, especially if also taking insulin or sulfonylureas.

When not to use

Do not use in patients with known hypersensitivity to vildagliptin, metformin or excipients; type 1 diabetes; diabetic ketoacidosis; severe renal impairment; acute conditions that may affect kidney function; severe infection, shock or severe dehydration; or other contraindications identified by the prescriber.

Special populations

• Pregnancy: Consult a healthcare professional before use during pregnancy or if planning pregnancy; diabetes treatment may need adjustment.
• Breastfeeding: Consult a healthcare professional before use while breastfeeding; treatment choice should be assessed by the prescriber.
• Fertility: Discuss fertility concerns or pregnancy planning with a healthcare professional before using anti-diabetic medicines.
• Liver: Use requires medical assessment in patients with liver disease or abnormal liver tests. Report yellowing of the skin or eyes, dark urine or persistent nausea.
• Kidney: Kidney function should be checked before and during treatment. Metformin-containing products may be unsuitable in severe renal impairment or acute conditions that reduce kidney function.
• Heart: Tell your doctor if you have heart failure, recent heart attack, circulation problems or breathing difficulties before using this medicine.
• Driving: Dizziness or low blood glucose may impair driving or operating machinery. Do not drive if you feel hypoglycaemic, dizzy, confused or unwell.
• Alcohol: Avoid excessive alcohol because it can increase the risk of metformin-associated lactic acidosis and may affect blood glucose control.

Interactions

Drugs:

• Tell your doctor about all medicines, especially insulin, sulfonylureas, diuretics, corticosteroids, beta-2 agonists, ACE inhibitors, medicines affecting kidney function and iodinated contrast agents.

Food:

• Take with meals unless advised otherwise. Maintain the diet plan recommended for diabetes management and avoid excessive alcohol.

Conditions:

• Kidney impairment, liver disease, heart failure, dehydration, severe infection, shock, diabetic ketoacidosis and conditions causing tissue hypoxia require medical review before use.

Storage and Disposal

• Store in a cool, dry place away from direct sunlight, heat and moisture. Keep in the original packaging until use.
• Store at room temperature unless the product packaging states a specific temperature requirement.
• Keep out of sight and reach of children.
• Do not throw unused medicine into household waste or wastewater. Ask a pharmacist how to dispose of expired or unwanted tablets safely.

Disclaimer

This information is for educational and product listing purposes only and does not replace professional medical advice. Use only as directed by a qualified healthcare professional. Always read the leaflet and follow the prescription. Seek urgent medical help for severe side effects, allergic reactions, lactic acidosis symptoms, severe abdominal pain or very low blood glucose.