Xalacom (0.005/0.5%) 2.5Ml Eye Drops

Overview

Xalacom 0.005%/0.5% Eye Drops is a prescription ophthalmic solution used to help lower raised pressure inside the eye, also called intraocular pressure. Each formulation strength combines latanoprost 0.005% with timolol 0.5%, two established antiglaucoma medicines that work through different mechanisms. It is generally prescribed for adults with open-angle glaucoma or ocular hypertension when single-agent treatment is not providing adequate pressure control.

Raised eye pressure can gradually damage the optic nerve and may lead to irreversible vision loss if not monitored and treated appropriately. Xalacom is not a cosmetic or routine lubricating eye drop; it should be used only under the supervision of an ophthalmologist or qualified healthcare professional.

Benefits

• Helps reduce elevated pressure inside the eye
• Supports management of open-angle glaucoma and ocular hypertension
• May reduce the need for separate latanoprost and timolol eye drops when both are prescribed
• Once-daily dosing may improve treatment routine when used as directed

Key Features

• Fixed-dose combination eye drop containing latanoprost 0.005% and timolol 0.5%
• Used for lowering raised intraocular pressure in suitable adult patients
• Ophthalmic solution supplied as a 2.5 ml bottle
• Prescription-only medicine for glaucoma and ocular hypertension management
• Combines a prostaglandin analogue with a beta-blocker

Dosage and How to Use

• How to use: Wash hands, remove contact lenses if worn, tilt the head back, pull down the lower eyelid and place one drop into the affected eye. Avoid touching the dropper tip. Close the eye and press the inner corner near the nose for about two minutes. Leave at least five minutes between different eye medicines.
• Administration: For ophthalmic use only. Apply into the affected eye or eyes. Do not inject or swallow. Avoid contamination of the dropper tip.
• Recommended dose: The usual adult dose is one drop in the affected eye or eyes once daily, or as prescribed by the doctor.
• Adult dose: One drop in the affected eye or eyes once daily, as prescribed.
• Pediatric use: Safety and efficacy in children and adolescents have not been established; use only if specifically prescribed by a specialist.
• Elderly use: The usual adult dose is generally used in elderly patients when clinically appropriate and prescribed.
• When to take: Use once daily at the same time each day, according to the schedule advised by the prescriber.
• With food: Not applicable; this is an ophthalmic eye drop and is not taken with food.
• Maximum daily dose: Do not use more than one drop in the affected eye or eyes once daily unless specifically directed by a doctor.
• Missed dose: If a dose is missed, skip it and continue with the next dose at the usual time. Do not use a double dose.
• Overdose: If too many drops are applied, rinse the eye with clean water if irritation occurs and seek medical advice. Accidental swallowing or symptoms such as slow heartbeat, dizziness, breathing difficulty, fainting, or severe weakness require urgent medical attention.

Specifications

Side Effects

Common side effects

• Eye redness
• Burning, stinging, itching, or irritation
• Watery eyes
• Temporary blurred vision
• Eye pain or discomfort
• Dry eye sensation
• Increased iris pigmentation
• Eyelash growth or darkening

Serious side effects (seek medical help)

• Severe allergic reaction
• Breathing difficulty or wheezing
• Chest pain or slow heartbeat
• Fainting or severe dizziness
• Severe eye pain or sudden vision changes
• Eye inflammation or swelling
• Signs of corneal damage or infection

Allergic reaction

Stop use and seek urgent medical help if signs of severe allergy occur, such as swelling of the face, lips, tongue, throat or eyelids, rash, severe itching, dizziness, or breathing difficulty.

Safety and Precautions

• Use only on prescription and under medical supervision.
• Tell your doctor if you have asthma, COPD, heart disease, slow heartbeat, heart block, heart failure, diabetes, thyroid disease, circulation problems, corneal disease, or a history of eye surgery.
• May cause temporary blurred vision after application.
• Do not stop treatment without medical advice, even if symptoms are not noticeable.
• Remove soft contact lenses before use and reinsert only after the interval recommended by a healthcare professional.
• Use separate eye medicines at least five minutes apart.
• Do not touch the dropper tip to the eye, eyelid, fingers, or other surfaces.
• Inform healthcare professionals before surgery that you use timolol-containing eye drops.

When not to use

Do not use in patients with known hypersensitivity to latanoprost, timolol, beta-blockers, or any component of the formulation. It is generally contraindicated in bronchial asthma or a history of bronchial asthma, severe chronic obstructive pulmonary disease, sinus bradycardia, certain heart blocks, overt cardiac failure, or cardiogenic shock unless a specialist determines otherwise.

Special populations

• Pregnancy: Use during pregnancy only if clearly advised by a healthcare professional after assessing potential benefits and risks.
• Breastfeeding: Consult a doctor before use while breastfeeding; do not use unless the prescriber considers it appropriate.
• Fertility: No patient-specific fertility advice can be given without medical assessment; consult a healthcare professional if planning pregnancy.
• Liver: Systemic exposure from eye drops is low, but patients with significant liver disease should inform their doctor before use.
• Kidney: Systemic exposure from eye drops is low, but patients with kidney disease should inform their doctor before use.
• Heart: Contains timolol, a beta-blocker that may affect heart rate and cardiac function. Use with caution and only on medical advice in patients with heart disease, slow pulse, heart block, low blood pressure, or heart failure.
• Driving: May cause temporary blurred vision after application. Do not drive or operate machinery until vision is clear.
• Alcohol: No specific food-alcohol dosing requirement applies to ophthalmic use, but avoid driving or risky activity if alcohol or the medicine affects alertness or vision.

Interactions

Drugs:

• Tell your doctor or pharmacist about all medicines being used, especially oral or eye beta-blockers, calcium channel blockers, antiarrhythmics, digoxin, medicines for high blood pressure, diabetes medicines, parasympathomimetics, and CYP2D6 inhibitors such as quinidine, fluoxetine, or paroxetine. Do not combine with other glaucoma eye drops unless prescribed.

Food:

• No clinically important food interaction is expected for ophthalmic use.

Conditions:

• Important disease considerations include asthma, COPD, bradycardia, heart block, heart failure, low blood pressure, peripheral circulation disorders, diabetes, hyperthyroidism, corneal disease, inflammatory eye disease, macular oedema risk, aphakia, pseudophakia, and history of herpetic keratitis.

Storage and Disposal

• Store according to the product label and pharmacist instructions. Keep the bottle tightly closed and protect it from contamination.
• Follow the temperature instructions printed on the pack or dispensing label.
• Keep out of sight and reach of children.
• Do not use after the expiry date or recommended in-use period after opening. Return unused or expired medicine to a pharmacy for safe disposal where possible.

Disclaimer

This information is for educational and product-content purposes only and does not replace professional medical advice. Use Xalacom only on prescription and exactly as directed by a qualified healthcare professional. Always read the label and patient leaflet. Seek medical advice for side effects, pregnancy, breastfeeding, other illnesses, interactions, or uncertainty about use.