Xaradol (325/37.5mg) 10 Tablets

Overview

Xaradol 325/37.5mg is a prescription pain-relief tablet that combines two analgesic ingredients: paracetamol 325mg and tramadol hydrochloride 37.5mg. It is generally used when pain is moderate to severe and a healthcare professional considers a combination medicine appropriate. Paracetamol helps reduce pain signals and fever-related discomfort, while tramadol is an opioid analgesic that acts on the central nervous system to change how pain is perceived.

This product is supplied as a 10-tablet pack and belongs to the pain, fever and muscle-relief medicine category. Because it contains tramadol, Xaradol should not be treated like an ordinary over-the-counter painkiller. It can cause sleepiness, dizziness, constipation, nausea, breathing-related risks in vulnerable patients, withdrawal symptoms and dependence if misused or taken for longer than advised.

Benefits

• May provide stronger pain relief than simple analgesics alone when clinically appropriate
• Combines non-opioid and opioid analgesic actions
• Useful for short-term symptomatic pain control as prescribed
• Single combination tablet may reduce the need for taking separate analgesic ingredients

Key Features

• Contains paracetamol 325mg plus tramadol hydrochloride 37.5mg
• Dual-action pain-relief formulation
• Used for moderate to severe pain under medical supervision
• 10-tablet pack
• Not suitable for self-medication due to opioid-related risks

Dosage and How to Use

• How to use: Swallow the tablet with water. Do not crush, misuse or take more frequently than prescribed. Avoid taking it with alcohol or with other paracetamol-containing products unless approved by a doctor or pharmacist.
• Administration: Oral tablet; swallow with water.
• Recommended dose: Use exactly as prescribed by a doctor. Dosing depends on pain severity, age, medical history, kidney and liver function, and other medicines. Do not exceed the prescribed dose.
• Adult dose: Adult dosing should be individualized and prescribed by a doctor. Do not self-adjust the dose.
• Pediatric use: Not generally recommended for children under 12 years. Use in adolescents only on medical advice.
• Elderly use: Elderly patients may be more sensitive to tramadol-related dizziness, sedation, constipation and breathing effects. Dose spacing or monitoring may be needed as advised by a doctor.
• When to take: Take only at the times advised by the prescribing doctor. If nausea occurs, taking after food may help, unless your doctor gives different instructions.
• With food: May be taken with or without food. Taking after food may reduce nausea in some patients.
• Maximum daily dose: For tramadol/paracetamol 37.5mg/325mg combination products, maximum dosing must be set by a healthcare professional and should not be exceeded. Do not take extra doses or combine with other paracetamol products.
• Missed dose: If used on a schedule and a dose is missed, take advice from your doctor or pharmacist. Do not double the next dose to make up for a missed dose.
• Overdose: Seek urgent medical help or contact a poison control/emergency service immediately. Overdose may cause severe drowsiness, breathing problems, seizures, unconsciousness or serious liver injury from paracetamol, even if symptoms are delayed.

Specifications

Side Effects

Common side effects

• Nausea
• Vomiting
• Dizziness
• Drowsiness
• Constipation
• Headache
• Dry mouth
• Sweating
• Fatigue

Serious side effects (seek medical help)

• Breathing difficulty or slow breathing
• Seizures
• Severe allergic reaction
• Extreme drowsiness or unconsciousness
• Signs of liver injury such as yellow skin or eyes, dark urine or severe abdominal pain
• Serotonin syndrome symptoms such as agitation, fever, tremor, sweating or fast heartbeat
• Dependence, withdrawal symptoms or misuse

Allergic reaction

Stop use and seek urgent medical help if rash, itching, swelling of the face/lips/tongue/throat, severe dizziness or breathing difficulty occurs.

Safety and Precautions

• Contains tramadol, an opioid analgesic with dependence, withdrawal and misuse potential
• May cause drowsiness, dizziness and impaired reaction time
• Avoid alcohol
• Do not combine with other paracetamol-containing medicines unless medically advised
• Seek urgent help for breathing difficulty, severe sleepiness, seizures, allergic reaction or overdose
• Use only for the prescribed person and condition
• Tell your doctor about liver, kidney, breathing, seizure, mental health or substance-use history
• Inform your doctor about all prescription, OTC and herbal medicines
• Use the lowest effective dose for the shortest duration advised by the doctor
• Do not stop long-term use suddenly without medical guidance

When not to use

Do not use if allergic to paracetamol, tramadol or any tablet ingredient. Avoid use in severe intoxication with alcohol, sleeping pills, opioids or psychotropic medicines, and in patients currently taking or recently taking MAO inhibitors, unless a doctor specifically determines otherwise.

Special populations

• Pregnancy: Use during pregnancy only if specifically prescribed after medical risk-benefit assessment. Tramadol may affect the baby, especially with repeated or late-pregnancy use.
• Breastfeeding: Do not use while breastfeeding unless a doctor specifically advises it. Tramadol may pass into breast milk and can cause serious effects in infants.
• Fertility: No product-specific fertility information is provided here. Consult a healthcare professional if planning pregnancy or undergoing fertility treatment.
• Liver: Paracetamol overdose can cause serious liver injury. Patients with liver disease, heavy alcohol use or those taking other paracetamol products need medical advice before use.
• Kidney: Use with caution in kidney impairment. Dose adjustment or longer dosing intervals may be required as advised by a doctor.
• Heart: Use with medical advice in patients with significant cardiovascular disease, low blood pressure or conditions worsened by dizziness, sedation or fainting.
• Driving: May cause drowsiness, dizziness, blurred concentration and delayed reaction time. Do not drive or operate machinery until you know how it affects you.
• Alcohol: Avoid alcohol. Alcohol increases the risk of severe sedation, breathing problems, liver toxicity and overdose.

Interactions

Drugs:

• Other opioids, sedatives, sleeping pills, benzodiazepines and muscle relaxants may increase sedation and breathing risk
• MAO inhibitors may cause serious interactions
• SSRIs, SNRIs, tricyclic antidepressants, migraine triptans, linezolid and other serotonergic medicines may increase serotonin syndrome or seizure risk
• Carbamazepine may reduce tramadol effect
• Warfarin and other anticoagulants may require monitoring due to paracetamol-related interaction concerns
• Other paracetamol-containing products increase overdose and liver-injury risk

Food:

• No specific food interaction is confirmed here. Avoid alcohol and check with a pharmacist before combining with herbal sedatives or products that may affect the liver or nervous system.

Conditions:

• Liver disease
• Kidney disease
• Seizure disorders or epilepsy
• Respiratory disease, sleep apnoea or severe asthma
• Opioid dependence or substance-use disorder
• Head injury or raised intracranial pressure
• Severe depression or use of interacting psychiatric medicines

Storage and Disposal

• Store in a cool, dry place away from direct sunlight, heat and moisture. Keep in original packaging until use.
• Store at room temperature unless the product label states otherwise.
• Keep out of the reach and sight of children, pets and anyone for whom the medicine was not prescribed.
• Do not use expired tablets. Ask a pharmacist about safe disposal of unused medicine, especially because it contains an opioid analgesic.

Disclaimer

This content is for product information only and is not a substitute for professional medical advice, diagnosis or treatment. Use Xaradol only as prescribed by a qualified healthcare professional. Do not start, stop, repeat or change the dose without medical guidance. Seek urgent medical help in case of overdose, severe side effects, allergic reaction, breathing difficulty, seizures or unusual drowsiness.