Xenglu-Lin (10/5Mg) 14 Tablets

Overview

Xenglu-Lin 10/5mg Tablets are an oral antidiabetic medicine used for the management of type 2 diabetes mellitus in adults. Each tablet contains two complementary active ingredients: empagliflozin 10mg and linagliptin 5mg. Empagliflozin belongs to the sodium-glucose co-transporter 2 inhibitor class, while linagliptin belongs to the dipeptidyl peptidase-4 inhibitor class.

This medicine is intended for patients who require dual oral therapy for blood sugar control. It is not a substitute for lifestyle measures, insulin where clinically required, or regular diabetes monitoring. Blood glucose, kidney function, hydration status and other risk factors should be reviewed by a healthcare professional before and during treatment.

Benefits

• Helps improve glycaemic control in adults with type 2 diabetes
• Supports blood glucose management through complementary mechanisms
• Can be used with diet and exercise as part of a diabetes care plan
• May help reduce long-term diabetes complication risk through improved blood sugar control

Key Features

• Contains empagliflozin 10mg plus linagliptin 5mg per tablet
• Oral antidiabetic combination for type 2 diabetes mellitus
• Dual SGLT2 inhibitor and DPP-4 inhibitor mechanism
• 14-tablet pack
• Use only as directed by a physician

Dosage and How to Use

• How to use: Swallow the tablet with water. Take at the same time each day, with or without food, and continue prescribed diet, exercise and glucose monitoring.
• Administration: Oral tablet; swallow whole with water unless advised otherwise by a healthcare professional.
• Recommended dose: Use exactly as prescribed by a physician. A common adult regimen for this combination strength is one 10mg/5mg tablet once daily in the morning.
• Adult dose: As prescribed; commonly one 10mg/5mg tablet once daily in the morning.
• Pediatric use: Safety and effectiveness in children and adolescents have not been established for this combination; use only if specifically prescribed by a specialist.
• Elderly use: Use with caution in elderly patients, especially those at risk of dehydration, low blood pressure, kidney impairment or recurrent infections.
• When to take: Usually once daily in the morning, as directed by the prescribing physician.
• With food: May be taken with or without food.
• Maximum daily dose: Do not exceed the dose prescribed by your doctor. For the empagliflozin/linagliptin combination, dose increases up to 25mg/5mg once daily may be considered only by a physician.
• Missed dose: Take the missed dose when remembered unless it is close to the next dose. Do not take two doses together to make up for a missed dose; follow your physician’s instructions.
• Overdose: Seek medical advice or emergency care immediately. Overdose may require monitoring and supportive treatment, especially for dehydration, low blood pressure, hypoglycaemia or electrolyte imbalance.

Specifications

Side Effects

Common side effects

• Increased urination
• Thirst
• Urinary tract infection
• Genital fungal infection
• Stuffy or runny nose
• Sore throat
• Low blood sugar when used with insulin or sulfonylureas

Serious side effects (seek medical help)

• Diabetic ketoacidosis
• Severe dehydration or low blood pressure
• Pancreatitis
• Severe urinary tract infection
• Fournier’s gangrene
• Serious allergic reaction
• Severe joint pain
• Bullous pemphigoid or blistering skin reaction
• Heart failure symptoms
• Lower limb infection, ulcers or amputation risk

Allergic reaction

Stop the medicine and seek urgent help if rash, hives, swelling of the face/lips/tongue/throat, breathing difficulty, skin peeling or severe allergic symptoms occur.

Safety and Precautions

• Not for type 1 diabetes or diabetic ketoacidosis
• May increase risk of ketoacidosis, dehydration, urinary infections and genital fungal infections
• Risk of hypoglycaemia may increase when combined with insulin or insulin secretagogues
• Assess kidney function and hydration status as advised by a doctor
• Inform your doctor about kidney disease, liver disease, heart failure, pancreatitis history, recurrent urinary infections or planned surgery
• Maintain adequate hydration unless fluid restriction has been advised
• Monitor blood glucose regularly
• Report symptoms of urinary infection, genital infection, severe abdominal pain or unusual tiredness promptly

When not to use

Known hypersensitivity to empagliflozin, linagliptin or any tablet ingredient | Use in diabetic ketoacidosis | Severe renal impairment, end-stage renal disease or dialysis unless a specialist advises otherwise

Special populations

• Pregnancy: Use during pregnancy only on medical advice. Diabetes treatment may need specialist adjustment during pregnancy.
• Breastfeeding: Consult a doctor before use while breastfeeding; the suitability of this combination should be assessed by a healthcare professional.
• Fertility: No patient-specific fertility information is available for this product; consult a doctor if planning pregnancy.
• Liver: Use with medical supervision in patients with liver disease or heavy alcohol use.
• Kidney: Kidney function should be assessed before and during treatment. This medicine may be unsuitable in significant renal impairment or dialysis.
• Heart: Discuss use with a doctor if you have heart failure, low blood pressure, cardiovascular disease or dehydration risk.
• Driving: Use caution when driving or operating machinery if dizziness, dehydration or low blood sugar symptoms occur.
• Alcohol: Limit or avoid alcohol unless your doctor says it is safe, as alcohol may worsen dehydration, hypoglycaemia or ketoacidosis risk.

Interactions

Drugs:

• Insulin and sulfonylureas may increase hypoglycaemia risk
• Diuretics may increase dehydration or low blood pressure risk
• Other glucose-lowering medicines may require dose review
• Tell your doctor about all prescription, OTC and herbal medicines

Food:

• No specific food restriction is universally required, but follow the diabetes meal plan advised by your doctor or dietitian.

Conditions:

• Type 1 diabetes
• Renal impairment
• Pancreatitis history
• Recurrent urinary tract or genital infections
• Heart failure
• Dehydration or low blood pressure
• Planned surgery or prolonged fasting

Storage and Disposal

• Store in a cool, dry place away from direct sunlight, heat and moisture. Keep in original packaging until use.
• Store at room temperature; avoid excessive heat and moisture.
• Keep out of the reach and sight of children.
• Do not use expired or damaged tablets. Ask a pharmacist how to safely dispose of unused medicine.

Disclaimer

This information is for educational purposes and does not replace medical advice. Use only as prescribed by a qualified healthcare professional. Always read the label and consult a doctor or pharmacist for diagnosis, dosing, interactions, pregnancy or breastfeeding advice, side effects, overdose or emergency concerns.