Xitaglip Plus (50/500mg) 14 Tablets

Overview

Xitaglip Plus 50/500mg is an oral antidiabetic medicine supplied as a pack of 14 tablets. The strength indicates a fixed-dose combination of sitagliptin 50mg and metformin 500mg, two medicines commonly used together to help improve blood glucose control in adults with type 2 diabetes mellitus. It is intended for patients whose healthcare professional considers combination therapy appropriate alongside diet, exercise, weight management, and regular blood sugar monitoring.

This medicine is not a substitute for lifestyle measures or routine diabetes care. It should be used only according to a doctor’s prescription, especially because diabetes treatment needs to be individualized according to blood glucose levels, kidney function, other medicines, age, diet, and risk of side effects.

Benefits

• Helps support blood glucose control in type 2 diabetes when prescribed
• Targets fasting and post-meal glucose through complementary mechanisms
• May reduce tablet burden compared with taking separate medicines
• Supports a wider diabetes care plan including diet, exercise, and monitoring

Key Features

• Fixed-dose combination of sitagliptin 50mg and metformin 500mg
• Oral tablet for type 2 diabetes management
• Pack of 14 tablets
• Combines DPP-4 inhibitor and biguanide therapy
• Use only under medical supervision

Dosage and How to Use

• How to use: Swallow the tablet with water. Do not crush, split, or chew unless advised by a pharmacist or doctor. Use consistently according to the prescribed schedule.
• Administration: Oral administration.
• Recommended dose: Take exactly as prescribed by your doctor. The dose depends on blood glucose control, kidney function, previous therapy, and individual tolerance.
• Adult dose: As prescribed by the treating physician based on clinical need and monitoring.
• Pediatric use: Use in children only if specifically prescribed by a pediatric specialist.
• Elderly use: Elderly patients may require careful kidney function assessment and medical monitoring before and during treatment.
• When to take: Take at the time directed by your prescriber. Metformin-containing medicines are commonly taken with meals to reduce stomach upset.
• With food: Usually taken with food when prescribed, particularly to reduce metformin-related stomach upset; follow your doctor’s instructions.
• Maximum daily dose: Do not exceed the dose prescribed by your doctor.
• Missed dose: Take the missed dose when remembered unless it is nearly time for the next dose. Do not take two doses together unless advised by a doctor.
• Overdose: Seek urgent medical help or contact a poison control/medical emergency service if overdose is suspected, especially if severe weakness, breathing difficulty, drowsiness, vomiting, or confusion occurs.

Specifications

Side Effects

Common side effects

• Nausea
• Vomiting
• Diarrhea
• Abdominal discomfort
• Loss of appetite
• Metallic taste
• Headache
• Mild upper respiratory symptoms

Serious side effects (seek medical help)

• Lactic acidosis symptoms
• Pancreatitis symptoms
• Severe allergic reaction
• Severe or persistent hypoglycemia when combined with other glucose-lowering medicines

Allergic reaction

Stop use and seek urgent medical help if you develop swelling of the face, lips, tongue, or throat, breathing difficulty, severe rash, blistering, or other signs of serious allergy.

Safety and Precautions

• Not for type 1 diabetes or diabetic ketoacidosis
• Use caution in kidney impairment, dehydration, severe infection, heart failure, or liver disease
• Seek urgent care for symptoms of lactic acidosis, pancreatitis, severe allergy, or severe hypoglycemia
• Do not start, stop, or change dose without medical advice
• Monitor blood glucose as advised
• Kidney function may need checking before and during treatment
• Inform your doctor about all medicines, supplements, and other diabetes treatments
• Avoid dehydration and discuss alcohol intake with your healthcare professional

When not to use

Do not use without medical advice if you have severe kidney disease, metabolic acidosis, diabetic ketoacidosis, severe dehydration, severe infection, or a previous serious reaction to sitagliptin or metformin.

Special populations

• Pregnancy: Use during pregnancy only if prescribed. Diabetes treatment in pregnancy requires close medical supervision.
• Breastfeeding: Use while breastfeeding only after medical advice, as diabetes therapy should be selected with maternal and infant safety in mind.
• Liver: Inform your doctor if you have liver disease or heavy alcohol use before taking this medicine.
• Kidney: Kidney function assessment is important before and during treatment because metformin-containing medicines may be unsuitable in significant kidney impairment.
• Heart: Inform your doctor if you have heart failure, recent heart attack, circulation problems, or severe illness before using this medicine.
• Driving: Avoid driving or operating machinery if you feel dizzy, shaky, confused, weak, or have symptoms of low blood sugar.
• Alcohol: Avoid or limit alcohol unless your doctor says it is safe, as alcohol may increase the risk of metformin-associated complications and low blood sugar.

Interactions

Drugs:

• Tell your doctor about all medicines you use, especially insulin, sulfonylureas, diuretics, corticosteroids, contrast dye procedures, other diabetes medicines, and medicines affecting kidney function.

Food:

• Take with meals if advised. Maintain a consistent diabetes meal plan and avoid excessive alcohol.

Conditions:

• Kidney disease, liver disease, heart failure, dehydration, severe infection, pancreatitis, metabolic acidosis, and diabetic ketoacidosis may affect suitability.

Storage and Disposal

• Store in a cool, dry place away from direct sunlight, heat, and moisture. Keep in original packaging.
• Store at room temperature unless the product pack states otherwise.
• Keep out of reach and sight of children.
• Do not dispose of unused tablets in wastewater or household waste. Ask a pharmacist about safe medicine disposal.

Disclaimer

This information is for general educational and product listing purposes only and is not a substitute for professional medical advice. Use only as prescribed by a qualified healthcare professional.